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Which enzyme exerts the most control on glycolysis?

Which enzyme exerts the most control on glycolysis?




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1 Answer

  1. Phosphofructokinase-1 (PFK-1) is the enzyme that exerts the most control on glycolysis. It catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key irreversible step that commits glucose to being metabolized in the glycolytic pathway.