True or false? Large proteins containing a nuclear localization signal (NLS) bind to the nuclear pore and enter the nucleus without any expenditure of energy.
Large proteins containing a nuclear localization signal (NLS) bind to the nuclear pore and enter the nucleus without any expenditure of energy
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FALSE. Cytoplasmic proteins called importins bind to large proteins containing an NLS and mediate their transport across the nuclear membrane through an active transport (energy-requiring) process.