During post-cardiac arrest care, the recommended duration of targeted temperature management (TTM) after reaching the target temperature range (32-36°C or 89.6-96.8°F) is generally 24 hours. This duration is based on guidelines and evidence supporting improved neurological outcomes and survival rates for patients who have experienced out-of-hospital cardiac arrest, particularly those with an initial rhythm of ventricular fibrillation or pulseless ventricular tachycardia.

After 24 hours of maintaining the target temperature, the patient should then undergo a gradual rewarming phase, typically at a rate of 0.25-0.5°C (0.45-0.9°F) per hour until they return to normothermia (37°C or 98.6°F).

It is essential to closely monitor and manage the patient’s physiological parameters throughout this process to minimize complications such as shivering, electrolyte imbalances, and hemodynamic instability.