Despite 2 Defibrillation attempts, the patient remains in ventricular fibrillation. Which drug and dose should you administer first to this patient?

If the patient remains in ventricular fibrillation (VF) despite 2 defibrillation attempts, the next step in the Advanced Cardiovascular Life Support (ACLS) algorithm is to administer epinephrine. The recommended drug and dose are:

• Epinephrine 1 mg IV/IO every 3-5 minutes during CPR.

This is crucial to increase coronary and cerebral perfusion pressure during resuscitation. After administering epinephrine, continue high-quality CPR and prepare for the next possible defibrillation attempt, re-assessing the rhythm after 2 minutes of CPR.

Epinephrine 1 mg.