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Which of the following is an example of negative feedback

Which of the following is an example of negative feedback?

A. High blood sugar stimulates the pancreas to secrete glucagon
B. Low blood calcium stimulates calcitonin secretion
C. Low body temperature stimulates shivering
D. High blood volume stimulates antidiuretic hormone (ADH) secretion




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  1. C. Low body temperature stimulates shivering

    Negative feedback mechanism is a physiologic response to detected change that opposes this change and returns the body to a ‘set normal’. When the weather is cold and body temps lower, shivering produces heat and raises the body temp back to its set normal.

    High blood sugar stimulates the pancreas to secrete glucagon (hormone that increases blood sugar) *POSITIVE FEEDBACK
    High blood sugar stimulates the pancreas to secrete insulin(lowers blood sugar) *NEGATIVE FEEDBACK

    Low blood calcium stimulates calcitonin (hormone that lowers blood calcium levels) secretion *POSITIVE FEEDBACK
    Low blood calcium stimulates parathyroid hormone (which mobilizes calcium from the bone & raises blood calcium back to norm) secretion *NEGATIVE FEEDBACK

    High blood volume stimulates antidiuretic hormone (ADH – increases blood volume) secretion *POSITIVE FEEDBACK
    Low blood volume stimulates ADH & ADH conserves fluid to return blood volume back to norm *NEGATIVE FEEDBACK