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A vial of reconstituted Adriamycin breaks inside a vertical flow hood. What should the technician do?

Anonymous

A vial of reconstituted Adriamycin breaks inside a vertical flow hood. What should the technician do?




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    3 Answers

    1. Quizzma Team

      clean up the spill with a spill kit

    3. Anonymous

      Dealing with a broken vial of a hazardous substance like reconstituted Adriamycin inside a vertical flow hood requires careful handling to ensure safety and proper cleanup. Here are the steps the technician should take:

      1. Personal Protection: Prioritize personal safety by putting on appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat or gown.
      2. Containment: Use absorbent material (such as spill pads or spill control pillows) to contain the spilled liquid within the hood and prevent it from spreading further.
      3. Ventilation: Keep the vertical flow hood running to maintain airflow and prevent the dispersion of any hazardous vapors.
      4. Isolation: Close off the area around the flow hood to prevent others from entering and potentially being exposed to the spilled substance.
      5. Cleanup: Carefully clean up the spilled liquid using appropriate spill cleanup materials and techniques. This may involve using absorbent pads or wipes to soak up the liquid, followed by proper disposal of the contaminated materials according to hazardous waste disposal guidelines.
      6. Decontamination: Thoroughly clean and decontaminate the affected area of the vertical flow hood following established procedures for handling hazardous spills.
      7. Documentation: Document the spill incident, including details such as the date, time, location, and actions taken for cleanup and decontamination. This information may be required for regulatory compliance or internal reporting purposes.
      8. Safety Review: Conduct a safety review to identify any factors that contributed to the spill and implement corrective measures to prevent similar incidents in the future.
    4. Anonymous

      If a vial of reconstituted Adriamycin (doxorubicin hydrochloride) breaks inside a vertical flow hood, the technician should follow these steps:

      1. Stop work immediately and avoid further disturbing the spill.
      2. Alert others in the area about the spill and ensure that no one enters the area until it is properly decontaminated.
      3. Leave the vertical flow hood running to contain the spill and prevent the spread of contamination.
      4. Follow the facility’s established procedures for handling cytotoxic drug spills, which typically involve: a. Putting on appropriate personal protective equipment (PPE) such as a chemotherapy gown, double chemotherapy gloves, and a respirator or mask. b. Using an approved cytotoxic spill kit to absorb and collect the spilled material. c. Wiping down the entire work area inside the hood with appropriate decontamination agents (e.g., sodium hypochlorite solution).
      5. Properly dispose of all contaminated materials, including the broken vial, absorbent pads, and contaminated PPE, in cytotoxic waste containers following hazardous waste disposal protocols.
      6. Document the spill incident, including the details of the spill, the actions taken, and the names of the individuals involved or potentially exposed.
      7. Report the spill to the appropriate supervisory or safety personnel and follow any additional procedures required by the facility for cytotoxic spill management.

      The safety of personnel and proper containment of the hazardous drug are the top priorities when dealing with a cytotoxic drug spill in a controlled environment like a vertical flow hood.

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