Dealing with a broken vial of a hazardous substance like reconstituted Adriamycin inside a vertical flow hood requires careful handling to ensure safety and proper cleanup. Here are the steps the technician should take:

1. Personal Protection: Prioritize personal safety by putting on appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat or gown.
2. Containment: Use absorbent material (such as spill pads or spill control pillows) to contain the spilled liquid within the hood and prevent it from spreading further.
3. Ventilation: Keep the vertical flow hood running to maintain airflow and prevent the dispersion of any hazardous vapors.
4. Isolation: Close off the area around the flow hood to prevent others from entering and potentially being exposed to the spilled substance.
5. Cleanup: Carefully clean up the spilled liquid using appropriate spill cleanup materials and techniques. This may involve using absorbent pads or wipes to soak up the liquid, followed by proper disposal of the contaminated materials according to hazardous waste disposal guidelines.
6. Decontamination: Thoroughly clean and decontaminate the affected area of the vertical flow hood following established procedures for handling hazardous spills.
7. Documentation: Document the spill incident, including details such as the date, time, location, and actions taken for cleanup and decontamination. This information may be required for regulatory compliance or internal reporting purposes.
8. Safety Review: Conduct a safety review to identify any factors that contributed to the spill and implement corrective measures to prevent similar incidents in the future.