The writer wants to add a sentence immediately before sentence 3 to connect the evidence and commentary provided in the second paragraph to the overall argument of the passage. Which of the following choices most effectively accomplishes this goal?

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While NASA astronauts are already experienced with the difficulties humans experience in outer space, these problems would be intensified on long-term missions.

The writer wants to add a sentence immediately before sentence 3 to connect the evidence and commentary provided in the second paragraph to the overall argument of the passage. Which of the following choices most effectively accomplishes this goal?

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